Osteoporosis is a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. It is responsible for most of the elderly fractures through decreasing the bone mass and mineral density.

Cell therapy is considered as a new approach to regenerate the bone tissue. Cells are able to secrete bioactive molecules and regulate the behavior of other cells in different host tissues.