Motor neurons are mostly just nerve cells that are responsible for managing muscles in the body to move. Motor Neuron Disease or “MND” is a rapidly progressive neurological disease which damages motor neurons that are essential for us being able to control our movement. Nerve cells from the brain transmit messages to the nerve cells in the spinal cord, which are then distributed to different muscles in the body.
Amyotrophic lateral sclerosis (ALS) – ALS is the most well-known type of neurological disorder in the MND family. This is a very rare disease that affects the muscles of the legs, arms, respiratory system, and mouth. Incidence rates for ALS are higher in men and women ages 50 and up.
Cell therapy has the capacity to renew the tissues. The body contains stem cell “niches,” i.e., specific regulatory microenvironments conducive to the maintenance, proliferation, and differentiation of stem cells. The clinical outcomes observed in ALS/MND are currently postulated to be due to various paracrine and somatic mechanisms that render a neurotrophic effect in various neurodegenerative diseases.