In recent years, with the rapid economic growth and the change of diet structure, the incidence of diabetes mellitus (DM) increased gradually. There is an alarming increase in the macro- and microvascular complications secondary to DM, in which Diabetic Foot Ulcer is one of the most common complications.
Cell therapy plays an important role in diabetic foot ulcer treatment. Growing evidence has demonstrated that cell transplantation can accelerate wound closure, ameliorate clinical parameters, and avoid amputation.